bs 2150r Search Results


tnf α  (Bioss)
93
Bioss tnf α
Schematic diagram of QCS-PEG@TA hydrogel preventing stricture after ESD operation. ( A ) The hydrogel is synthesized via gelation of quaternized chitosan (QCS) and 8-arm polyethylene glycol (8-arm PEG) with the addition of triamcinolone acetonide (TA), as depicted by molecular diagrams. ( B ) Upon endoscopic injection into the submucosal layer of a porcine esophagus, the hydrogel forms a biocompatible barrier, releasing therapeutic agents locally. ( C ) Anti-inflammatory effects are demonstrated by increased M2 macrophage activity and <t>reduced</t> <t>TNF-α/β</t> levels, while anti-fibrotic action is evidenced by decreased collagen I deposition and α-SMA secretion. Such a dual-pathway regulation addresses post-ESD stenosis, providing a translational approach for the treatment and management of esophageal stricture in clinical settings.
Tnf α, supplied by Bioss, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tnf α/product/Bioss
Average 93 stars, based on 1 article reviews
tnf α - by Bioz Stars, 2026-03
93/100 stars
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tnf alpha polyclonal antibody  (Bioss)
91
Bioss tnf alpha polyclonal antibody
Schematic diagram of QCS-PEG@TA hydrogel preventing stricture after ESD operation. ( A ) The hydrogel is synthesized via gelation of quaternized chitosan (QCS) and 8-arm polyethylene glycol (8-arm PEG) with the addition of triamcinolone acetonide (TA), as depicted by molecular diagrams. ( B ) Upon endoscopic injection into the submucosal layer of a porcine esophagus, the hydrogel forms a biocompatible barrier, releasing therapeutic agents locally. ( C ) Anti-inflammatory effects are demonstrated by increased M2 macrophage activity and <t>reduced</t> <t>TNF-α/β</t> levels, while anti-fibrotic action is evidenced by decreased collagen I deposition and α-SMA secretion. Such a dual-pathway regulation addresses post-ESD stenosis, providing a translational approach for the treatment and management of esophageal stricture in clinical settings.
Tnf Alpha Polyclonal Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tnf alpha polyclonal antibody/product/Bioss
Average 91 stars, based on 1 article reviews
tnf alpha polyclonal antibody - by Bioz Stars, 2026-03
91/100 stars
  Buy from Supplier
msr1 polyclonal antibody  (Bioss)
93
Bioss msr1 polyclonal antibody
Schematic diagram of QCS-PEG@TA hydrogel preventing stricture after ESD operation. ( A ) The hydrogel is synthesized via gelation of quaternized chitosan (QCS) and 8-arm polyethylene glycol (8-arm PEG) with the addition of triamcinolone acetonide (TA), as depicted by molecular diagrams. ( B ) Upon endoscopic injection into the submucosal layer of a porcine esophagus, the hydrogel forms a biocompatible barrier, releasing therapeutic agents locally. ( C ) Anti-inflammatory effects are demonstrated by increased M2 macrophage activity and <t>reduced</t> <t>TNF-α/β</t> levels, while anti-fibrotic action is evidenced by decreased collagen I deposition and α-SMA secretion. Such a dual-pathway regulation addresses post-ESD stenosis, providing a translational approach for the treatment and management of esophageal stricture in clinical settings.
Msr1 Polyclonal Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/msr1 polyclonal antibody/product/Bioss
Average 93 stars, based on 1 article reviews
msr1 polyclonal antibody - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier

Image Search Results


Schematic diagram of QCS-PEG@TA hydrogel preventing stricture after ESD operation. ( A ) The hydrogel is synthesized via gelation of quaternized chitosan (QCS) and 8-arm polyethylene glycol (8-arm PEG) with the addition of triamcinolone acetonide (TA), as depicted by molecular diagrams. ( B ) Upon endoscopic injection into the submucosal layer of a porcine esophagus, the hydrogel forms a biocompatible barrier, releasing therapeutic agents locally. ( C ) Anti-inflammatory effects are demonstrated by increased M2 macrophage activity and reduced TNF-α/β levels, while anti-fibrotic action is evidenced by decreased collagen I deposition and α-SMA secretion. Such a dual-pathway regulation addresses post-ESD stenosis, providing a translational approach for the treatment and management of esophageal stricture in clinical settings.

Journal: Regenerative Biomaterials

Article Title: Triamcinolone acetonide-loaded chitosan-polyethylene glycol hydrogel for preventing esophageal stricture post-endoscopic submucosal dissection

doi: 10.1093/rb/rbag002

Figure Lengend Snippet: Schematic diagram of QCS-PEG@TA hydrogel preventing stricture after ESD operation. ( A ) The hydrogel is synthesized via gelation of quaternized chitosan (QCS) and 8-arm polyethylene glycol (8-arm PEG) with the addition of triamcinolone acetonide (TA), as depicted by molecular diagrams. ( B ) Upon endoscopic injection into the submucosal layer of a porcine esophagus, the hydrogel forms a biocompatible barrier, releasing therapeutic agents locally. ( C ) Anti-inflammatory effects are demonstrated by increased M2 macrophage activity and reduced TNF-α/β levels, while anti-fibrotic action is evidenced by decreased collagen I deposition and α-SMA secretion. Such a dual-pathway regulation addresses post-ESD stenosis, providing a translational approach for the treatment and management of esophageal stricture in clinical settings.

Article Snippet: Afterwards, the slices were incubated with IL-1β (Cat No. AF7209, Beyotime), TNF-α (Cat No. bs-2150R, Bioss), TNF-β (Cat No. bs-0093R, Bioss), Cytokeratin 5 (Cat No. bs-1060R, Bioss), CD31 (Cat No. bs-0195R, Bioss), Collagen I (Cat No. bs-0578R, Bioss), α-SMA (Cat No. bsm-33187M, Bioss) overnight at 4°C, respectively.

Techniques: Synthesized, Injection, Activity Assay

Cytotoxicity, macrophage polarization and cell migration of hydrogel. The cytotoxicity was evaluated by ( A ) live/dead staining on the first, second and third day after processing with different materials and ( B ) CCK-8 assay ( n = 5). ( C ) Flow cytometry analysis of F4/80 and CD206 expression. ( D ) Percentage of M2 macrophages (F4/80 + CD206 + , n = 3). ( E ) TNF-α and ( F ) TGF-β in cell supernatant after different treatments detected by ELISA ( n = 3). ( G ) Cell migration assay and ( H ) migration ratio of L929 cells incubation with different treatments for 48 h ( n = 3). * P < 0.05, ** P < 0.01 and *** P < 0.001.

Journal: Regenerative Biomaterials

Article Title: Triamcinolone acetonide-loaded chitosan-polyethylene glycol hydrogel for preventing esophageal stricture post-endoscopic submucosal dissection

doi: 10.1093/rb/rbag002

Figure Lengend Snippet: Cytotoxicity, macrophage polarization and cell migration of hydrogel. The cytotoxicity was evaluated by ( A ) live/dead staining on the first, second and third day after processing with different materials and ( B ) CCK-8 assay ( n = 5). ( C ) Flow cytometry analysis of F4/80 and CD206 expression. ( D ) Percentage of M2 macrophages (F4/80 + CD206 + , n = 3). ( E ) TNF-α and ( F ) TGF-β in cell supernatant after different treatments detected by ELISA ( n = 3). ( G ) Cell migration assay and ( H ) migration ratio of L929 cells incubation with different treatments for 48 h ( n = 3). * P < 0.05, ** P < 0.01 and *** P < 0.001.

Article Snippet: Afterwards, the slices were incubated with IL-1β (Cat No. AF7209, Beyotime), TNF-α (Cat No. bs-2150R, Bioss), TNF-β (Cat No. bs-0093R, Bioss), Cytokeratin 5 (Cat No. bs-1060R, Bioss), CD31 (Cat No. bs-0195R, Bioss), Collagen I (Cat No. bs-0578R, Bioss), α-SMA (Cat No. bsm-33187M, Bioss) overnight at 4°C, respectively.

Techniques: Migration, Staining, CCK-8 Assay, Flow Cytometry, Expressing, Enzyme-linked Immunosorbent Assay, Cell Migration Assay, Incubation

QCS-PEG@TA Hydrogel reduced the expression of inflammatory factors, angiogenesis and collagen deposition. Immunohistochemistry staining ( A ) and quantitative statistics ( B ) of TNF-α, TNF-β, CD31, α-SMA, collagen-I and CK5 on Day 7 postsurgery (scale bar, 100 μm; n = 3). Immunohistochemistry ( C ) and quantitative statistics ( D ) of TNF-α, TNF-β, CD31, α-SMA, collagen-I and CK5 on Day 28 postsurgery (scale bar, 1 mm; n = 3). * P < 0.05 and ** P < 0.01.

Journal: Regenerative Biomaterials

Article Title: Triamcinolone acetonide-loaded chitosan-polyethylene glycol hydrogel for preventing esophageal stricture post-endoscopic submucosal dissection

doi: 10.1093/rb/rbag002

Figure Lengend Snippet: QCS-PEG@TA Hydrogel reduced the expression of inflammatory factors, angiogenesis and collagen deposition. Immunohistochemistry staining ( A ) and quantitative statistics ( B ) of TNF-α, TNF-β, CD31, α-SMA, collagen-I and CK5 on Day 7 postsurgery (scale bar, 100 μm; n = 3). Immunohistochemistry ( C ) and quantitative statistics ( D ) of TNF-α, TNF-β, CD31, α-SMA, collagen-I and CK5 on Day 28 postsurgery (scale bar, 1 mm; n = 3). * P < 0.05 and ** P < 0.01.

Article Snippet: Afterwards, the slices were incubated with IL-1β (Cat No. AF7209, Beyotime), TNF-α (Cat No. bs-2150R, Bioss), TNF-β (Cat No. bs-0093R, Bioss), Cytokeratin 5 (Cat No. bs-1060R, Bioss), CD31 (Cat No. bs-0195R, Bioss), Collagen I (Cat No. bs-0578R, Bioss), α-SMA (Cat No. bsm-33187M, Bioss) overnight at 4°C, respectively.

Techniques: Expressing, Immunohistochemistry, Staining